MetaPred2CS Web server

MetaPred2CS Web server is a meta-predictor based on Support Vector Machine (SVM) that combines 6 individual sequence based protein-protein interaction prediction methods to predict prokaryotic two-component system protein-protein interactions (PPIs). The methods implemented in MetaPred2CS are 2 co-evolutionary methods: in-silico two hybrid (i2h) and mirror tree (MT) methods and 4 genomics context based methods: phylogenetic profiling (PP), gene fusion (GF), gene neighbourhood (GN) and and gene operon methods (GO).

Please check help page before uploading input files as the fasta files require a specific header.

Input Files
Please upload fasta file for first protein:

OR paste your proteins sequence here :


Please upload fasta file for second protein:

OR paste your proteins sequence here: